Pseudomyxoma Peritonei (PMP) Research

PMP or Pseudomyxoma peritonei is a rare tumor that pervades the peritonium with a jelly like substance creating blockages. It can be malignant and has been found to have a bacterial component. Researchers have concluded that surgery followed by chemotherapy is a successful treatment in some cases. Molecular biologists at UCLA determined the genes MUC2 and MUC5AC are responsible for the mucin produced by the tumors. Since increased bacterial presence is presented in malignancy, researches also determined there is some degree of successful treatment with antibiotics.

Key Takeaways:

  • Pseudomyxoma peritonei (PMP) is a type of tumor characterized by the progressive dissemination of jelly-like ascites and mucinous tumor in the peritoneum.
  • In 2008, there was found a link between certain bacterial infections and this increase of mucus in the peritoneum.
  • While there is research toward a cure, it is relative rare, with an approximate annual occurrence of 0.5 to 1 cases in every 100,000 people.

“the results obtained showed that the PMCA patients receiving antibiotics have lesser bacterial density, but this is not so in DPMA patients”