It is becoming increasingly clear that boron, a trace mineral, is necessary for defending men against potentially fatal prostate cancer.
Men suffer the most fatalities due to prostate cancer.
As we age, our likelihood of developing prostate cancer grows, and it is generally fatal when it spreads beyond the prostate.1.
A variety of nutrients, minerals included, can be beneficial in decreasing the possibility of being diagnosed with prostate cancer and bettering prostate wellbeing. These include vitamins, minerals, and other food extract nutrients.
No one thing can guarantee complete protection from developing prostate cancer. By consuming a combination of these essential nutrients, your risk of developing prostate cancer is decreased.
It is assumed that you are avoiding foods, such as cow dairy products, that could promote prostate cancer.
Recent research has shown that boron-based compounds can selectively attack and destroy prostate cancer cells while leaving healthy cells intact. This article will take a look at the potential of boron to lower the chances of getting prostate cancer and will review some of the key advantages of taking this supplement.
PSA is an abbreviation for prostate-specific antigen, a protein produced in the largest quantities in the prostate gland. The goal of having a man’s blood tested for PSA is to identify prostate cancer before it becomes too serious, where treatment is more likely to be successful. The PSA test can also be used to gauge the effectiveness of various treatment options for prostate cancer.
Up to this point, Prostate-Specific Antigen has exclusively been looked at as a measure in blood showing the presence of prostate cancer, infection, or inflammation. New research shows that PSA could have other properties than merely indicating prostate health. It looks like PSA may be a factor in the spread and development of prostate cancer, giving rise to fresh options for preventing and treating this widespread illness.
There is a substantial amount of research indicating a correlation between a high consumption of certain nutrients and a lower rate of prostate cancer. Some research indicates that these nutrients may be useful in managing more advanced forms of the condition.
Researchers are now discovering that certain minerals are capable of decreasing or halting the activity of PSA in the prostate gland. The recent data hints that PSA might be linked to the development and spread of prostate cancer, which emphasizes the potential benefits of consuming certain nutrients with anti-PSA activity. This explains why men who consume such nutrients stand a lower chance of being diagnosed with the disease and experience its progression at a slower rate.
Staggering Statistics on Prostate Cancer
Cells in the prostate gland are very likely to experience gene mutation, whereas other tissues in the same area of the body, like the seminal vesicles, demonstrate a much lower frequency of primary tumors.
Autopsies show that around a third of men aged 40-49 and as many as 70% of men aged 80 or over have prostate cancer visible under the microscope. Most men do not get to the point of having a diagnosed disease, which would mean that there are regulators in place that help to keep the size/number of prostate cancer cells in check.
It looks like it is now possible to partially control certain genes that generally let cells divide uninhibitedly and form prostate cancer, which can then extend, infiltrate, and advance to other body parts. It is now even more essential for males to check their blood PSA levels to discover prostate cancer in its initial phases as a result of these breakthroughs.
Treating Advanced Prostate Cancer with Lycopene
Cancer confined to the prostate gland is usually curable. Studies in the medical field show that if prostate cancer is not treated, the cells of the tumor will keep multiplying. A larger amount of tumors is linked with a genetic alteration that is probably the cause of prostate cancer that is no longer affected by hormones. Once the cells in the prostate have mutated into a form that can resist hormone therapy, metastatic prostate cancer is normally diagnosed and the individual must endure an arduous battle for their life.
A research project involving 20 individuals suffering from metastasized, estrogen-immune prostate cancer involved each patient being administered 10 milligrams of lycopene per day for a period of three months. No other treatment was given. One patient experienced a full recovery, which was defined as having a PSA (of under 4 ng/ml) and no indication of the ailment for eight weeks. 30% of the patients experienced a partial response, consisting of a decrease in PSA by half and a lessening of symptoms, including bone discomfort if any. Ten patients (50%) showed no changes in the disease, while three (15%) had a worsening condition. An impressive 63 percent (10 out of 16) of those experiencing bone pain were able to decrease the amount of pain-reducing drugs they utilized daily. The research discovered that utilizing lycopene is an efficient and safe option for the management of prostate cancer which does not respond to hormone therapy.
In an additional study of 54 persons diagnosed with prostate cancer that had spread, 27 were given castration treatment only, while the remaining 27 were castrated and given 2 milligrams of lycopene twice a day. The removal of testes leads to a decrease in testosterone quantities and is a therapy for those who suffer from prostate cancer that relies upon androgen. After a period of half a year, the size of the PSA dropped greatly in both groups and even more so in the one that took lycopene. After two years, forty percent of the group from which the testicles had been removed showed a decrease in PSA of less than 4 ng/ml, while seventy-eight percent of the lycopene group had the same reduction. The results of the bone scans revealed that twice the amount of patients in the lycopene-in-conjunction-with-castration group experienced complete remission when compared to the sole-castration men.
The author concluded, “Adding lycopene to orchidectomy (castration) produced a more reliable and consistent decrease in serum PSA level; it not only shrinks the primary tumor but also diminishes the secondary tumors, providing better relief from bone pain and lower urinary tract symptoms, and improving survival compared with orchidectomy alone.” What is impressive about these two studies is that only small doses of lycopene (4-10 mg/day) were used. It is remarkable that such constructive outcomes came from the administering of small amounts of lycopene to patients in an advanced stage of prostate cancer; additional research in this area is fully justified.
Boron Shrinks Prostate Tumors, Reduces PSA in Mice
It has been mentioned before that most healthcare professionals view the PSA test as an effective laboratory indicator for diagnosing prostate cancer. At the microscopic level, PSA plays a role as a stimulant for the expansion of the prostate gland. An example of one process that happens is PSA’s ability to break down proteins that provide structure and support to the cells, including fibronectin and laminin. The act conducted by PSA could very well encourage the growth and spreading of tumors. Possible rephrasing: Possible tumor facilitation may be conferred by PSA through the liberation of insulin-like growth factor 1 (IGF-1) from its binding protein (BP-3), which could consequently create higher levels of IGF-1 in the surrounding environment, eventually leading to the growth of a tumor. In order to have an appreciation of the type of adversary we are facing with cancer cells, it is essential to grasp that a tumor cell is operational and produces things that help its expansion, encroachment and propagation.
Gallardo-Williams and their team of researchers have uncovered that boric and boronic acids have a major effect on suppressing the breakdown of fibronectin that was caused by the enzyme PSA. In a different examination that involved mice, the same authors employed immunohistochemistry dyeing of tissues to demonstrate that the expression of IGF-1 in tumors was considerably curtailed by boric acid. The effects of both a small dosage and a large dosage of boron showed that the average Prostate-Specific Antigen (PSA) numbers decreased by 87%, while the average size of the tumors reduced by 31.5%. It was observed that the groups supplied with boron had a much smaller number of mitotic figures. Mitotic figures reflect DNA synthesis and proliferative activity.
A recent study revealed that boron slowed down the growth of two prostate cancer cell types in proportion to the dosage. The two cell lines were DU-145, which is androgen-independent, and LNCaP, which is androgen-dependent. It was revealed in a report from the University of California, Los Angeles that men with the highest intake of boron through their diet were found to have lowered their risk of prostate cancer by 54%, compared to those with the least boron consumption. This finding is supported by animal and cell line studies and is thought to be applicable to humans. Taking into account the limited sample size and the research design, the authors acknowledge that this connection should be taken with a grain of salt. Nonetheless, these results demand more study. If scientists can duplicate the findings from animal studies in human patients, using boron with a dosage between 6 and 15 milligrams a day could turn into a cheep and effective adjunct treatment.
Can Boron Lower PSA?
In addition, boron has been found to lower PSA. It used to be thought that PSA was only an indicator of benign prostatic hyperplasia and prostate cancer.
Recent studies indicate that having higher PSA levels can actually lead to an increase in prostate cancer.
Having enough boron has been linked to a lower risk of prostate cancer by 64%, but it can be hard to get enough of it from what you eat.
There is hardly any boron found in food, particularly if not grown using organic methods.
This points to the fact that boron-containing dietary supplements, which are inexpensive, may be a major help to elderly males who are vulnerable to prostate cancer, as well as conferring other health advantages from this necessary mineral.
What Are the Benefits of Boron?
In 2001, a research on the eating habits of individuals with prostate cancer was conducted, with 76 persons suffering from the disease and 7,651 healthy individuals that served as the control group.
The research concluded that the males who consumed the highest amount of boron in their diet were 64% less inclined to acquire prostate cancer in comparison to those who had the least amount.
More clinical tests have been done that have yielded comparable outcomes.
A research project looked into the boron consumption among 95 individuals who had prostate cancer, as well as 8,720 males who did not have the medical condition. That study was controlled for many other factors.
The study revealed that males who ingested the highest amount of boron had a 54% less probability of developing prostate cancer as compared to those who had the lowest intake.
They also discovered that consuming more boron as part of one’s diet was associated with a decreased chance of getting prostate cancer. It was verified that the drop in numbers correlated exactly with the boron intake. Scientists were encouraged by these epidemiological findings.
There was an obvious link between eating foods high in boron and a decreased chance of getting prostate cancer. Researchers then conducted experiments to determine if taking additional boron would prevent prostate cancer. Initial animal studies indicate that the answer is yes.
Researchers discovered that swallowing different levels of a boron-containing liquid significantly diminished the size of the tumor.
The results also demonstrated a decrease in prostate-specific antigen (PSA), the major protein made in the prostate gland, which may possibly be linked to the anti-cancer properties.
The scientists in this study utilized a technique of giving laboratory animals a liquid solution with boron in it. This caused the size of their prostate tumors to shrink by up to 38%, with an average reduction of 25%.
It was surprising to find that PSA levels fell between 86% to 89% in the animals given boron supplements.
The results indicated that the addition of boron could be beneficial in terms of both prevention and treatment; it could potentially reduce the size of prostate tumors and decrease the amount of PSA.
Using Boron for Treatment
A 2014 study revealed that a compound with boron in it had the capability of causing cell death in prostate cancer cells, as published in Tumor Biology. They determined that boron could be paramount in the management of prostate cancer.
The findings of the numerous research projects concerning boron and its impact on prostate cancer and metastasis lead to the conclusion that taking a boron supplement would be advantageous. It is better to depend on a dependable supply of boron instead of depending on the erratic and meager quantities present in vegetables.
Boron is an important factor to consider when attempting to avoid prostate cancer and keep PSA levels at an ideal point. Research has recently been revealed to indicate that boron is an additional way to protect against the spread of prostate cancer.
Boron is concentrated in the bone. Research projects that have just started to appear show that boron may provide an additional barrier against the signs of this prostate cancer- in the bones.
Is Boron Good for Bones?
The greatest risk posed by prostate cancer is its potential to metastasize to the bone. Approximately 80% of all metastases from prostate cancer start in the bones.
The most typical sites for them to arise are in the back, hips, ribs, head and upper part of the thigh bone.